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学業成績のリスト

創業者は1991年に日本に留学して以来、基礎皮膚科学研究、細胞生理学・薬理学研究に熱心に取り組んでおり、皮膚細胞の特徴や分泌されるサイトカインの役割に精通し、その影響を探っています。細胞や動物への天然物抽出物。老化防止効果の影響が発見されました。研究結果は多くの学術論文を発表しています。

代表的な研究成果

1,Yonghao Qi1, Ambara R. Pradipta and Lijun Zhou1, *,Cinchonine Induces Apoptosis of HeLa and A549 Cells Through Targeting TRAF6. J Exp Clin Canc Res. 2017,Feb 23;36(1):35. doi: 10.1186/s13046-017-0502-8.  
2,Miao Li, Yonghao Qi and Lijun Zhou*, N6-Isopentenyladenosine inhibits cervical cancer cell proliferation through suppression of TAK1 and AKT activation. Tumor Biol. 2017. Mar;39(3), doi: 10.1177/1010428317695966.
3,Li Miao, Zhou Lijun*, The Progress of Research on the Relationship between TRAF6 and Tumor. Biotechnol Bull.  2017, 33(6),24-31. 
4,Wenjuan Liu, Yonghao Qi, Lingyu Liu, Yu Tang, Jing Wei, and Lijun Zhou*, Suppression of tumor cell proliferation by quinine via the inhibition of the tumor necrosis factor receptor‑associated factor 6‑AKT interaction. Molecular Medicine Reports. 14(3) • July 2016 with 15 Reads, DOI: 10.3892/mmr.2016.5492
5,Yonghao Qi, Miao Li, Lian Xu, Zhijing Chang, Xiong Shu and Lijun Zhou*, Therapeutic role of human hepatocyte growth factor (HGF) in treating hair loss. PeerJ. 4:e2624,DOI:10.7717/peerj.2624. November 1, 2016,PubMed 27833804。
6,Lulu Lu, Xuan Zhao, Jianyong Zhang, Miao Li, Yonghao Qi, Lijun Zhou*,
Calycosin promotes lifespan in Caenorhabditis elegans through insulin signaling pathway via daf-16, age-1 and daf-2. J Biosci Bioeng. 2017, 1:124.

7,Xuan Zhao, Lulu Lu, Yonghao Qi, Miao Li, Lijun Zhou*, Emodin extends lifespan of Caenorhabditis elegans through insulin/IGF-1 signaling pathway depending on DAF-16 and SIR-2.1. Bioscience, Biotechnology and Biochemistry. Epub 2017 Aug 23. 0916-8451 (Print) 1347-6947 (Online). Oct; 81(10):1908-1916. doi: 10.1080/09168451.2017.1365592.
8,Xue Wang, Jiaolong Zhang, Lulu Lu, Lijun Zhou*, The Longevity Effect of Echinacoside in Caenorhabditis elegans Mediated Through daf-16. Bioscience, Biotechnology and Biochemistry. 2015, 79-10, 1676-1683. DOI:10.1080/09168451.2015.1046364
9,Jiaolong Zhang, Lulu Lu, and Lijun Zhou*, Oleanolic acid activates daf-16 to increase lifespan in C.elegans. Biochem Biophys Res Commun, 2015, 1-7. 468(4):843-9DOI: 10.1016/j.bbrc.2015.11.042
10,Lian Xu, Xiong Shu, Zhijing Chang,  Wenjuan Liu, Xue Wang, Lijun Zhou*, Construction of hepatocyte growth factor eukaryotic expression plasmid and expression in fibroblasts. Prog Mod Biomed. 2015, 1, 21
11,Lian Xu, Lijun Zhou* , Chinese Complex herb formulas promote hair follicle growth by stimulating proliferation of dermal papilla cells and expression of hepatocyte growth factor. Prog Mod Biomed. 2014, 22, 21.
12,Yingqian Sun, Shuxin Wan*, Lijun Zhou*, Use of Response Surface Methodology to Optimize Chitosan Microparticles for Sustained Release of Curcumin. Lat Am J Pharm. 2012, 31(4).
13,Pei Liu, Lijun Zhou*, Yanfang Su, Shilun Yan, The gold of gentian total saponins preparation and preliminary study of inhibited cervical cancer.  China Pharmacy. 2011sep.Vol.22No.35.
14,Zhijing Chang, Lijun Zhou*. The Investigation on the Related Genes of Crohn’s Disease. Prog Mod Biomed. 2013, 3.
Erfu Yan, Lian Xu, Wenjuan Liu, Lijun Zhou*.Novel Anticancer Drug Molecular Target STAT3 and Its Advancement. Prog Mod Biomed. 2013, 2.
15,Lijun Zhou*, Wenjuan Liu, Yonghao Qi, Miao Li, SOCS3 Negatively Regulates AKT through JNK and STAT3 SignalPathways. China Biotechnology. 35(9)2015,50-56 (Series No. 282), doi:10.13523/j.cb.20150908.
16,Lijun Zhou, Touru Tatesita, Itirou Ono, Humie Kaneko*, Effects of TGF-beta 1 on fibroblasts from normal and hypertrophic scarred skin. Progress in Medicine. 1998, 8: 161-163.
17,Lijun Zhou, Masaharu Inowe, Itirou Ono,Humie Kaneko*, Effects of prostaglandin E1 on cultured dermal fibroblast from normal and hypertrophic scarred skin. J Dermatol Sci. 1997, 14: 217-224.
18,Lijun Zhou, Masaharu Inowe, Itirou Ono, Humie Kaneko*, The mode of action of prostaglandin(PG)I1 analog, SM-10906, on fibroblasts of hypertrophic scars is similar to PGE1 in its potential role of perverting from scar formation. Exp Dermatol. 1997, 6: 314-320.
19,Lijun Zhou, Masaharu Inowe, Itirou Ono,Humie Kaneko*, Role of transforming growth factor-beta 1 in fibroblasts derived form normal and hypertrophic scarred skin. Arch Dermatol Res. 1997, 289: 646-652.
20,Itirou Ono*, Lijun Zhou, Stimulatory effects of dibutyryl cyclic adenosine monophosphate on cytokine production by keratinocytes and fibroblasts. British journal of dermatology 143 (3) 2000, 9: 506-512.
21,Itirou Ono*, Lijun Zhou, Development of a chronic skin defect model and a study of cytokine secretion using the model. Wound Repair and Regeneration 8 (4) 2000,7-8: IDS Number: 351KU.
22,Itirou Ono*, Lijun Zhou, Study on the secretion of cytokines from osteoblasts stimulated with prostaglandin E1. Journal of Craniofacial Surgery 11(2),2000,3: 189-193.
23,Itirou Ono*, Lijun Zhou.Effects of a collagen matrix containing prostaglandin E1 on wound contraction. Journal or Dermatol Scie. 25(3),2001,2: 106-115.
24,Lijun Zhou ,Touru Tatesita,Itirou Ono,Humie Kaneko ,EffectsofTGF-beta 1 on fibroblasts from normal and hypertrophic scarred skin.,JSID,1996,161-163。

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